Have you been told you have penicillin allergy? Did your parents tell you that you had a reaction as an infant or child, so you should never take it again? Has it been so long since you had a reaction to penicillin that you don’t remember what happened? If you fit any of these descriptions or are just not sure if you have penicillin allergy, there’s good news for you: Chances are, you probably don’t have it.

Between 10 to 20 percent of Americans believe they have a penicillin allergy, but a recent study at Mayo Clinic found that only 10 percent of those people are truly penicillin allergic. In other words, 9 out of 10 people who think they have penicillin allergy are avoiding it for no reason. Even in people with documented allergy to penicillin, only about 20 percent are still allergic 10 years after their initial allergic reaction. It’s not necessarily a permanent condition.

Why is this important? Aren’t there many other antibiotics you can use if you have penicillin allergy? Penicillin has been around since 1928. Penicillin and its related medicines include amoxicillin, methicillin and amoxicillin-clavulnate. These medicines are highly effective treatments for many bacterial infections, such as strep throat and ear infections. Of course, there are alternative antibiotics, but these are often much more expensive and carry a higher risk of side effects. Typically, these alternative antibiotics are broad-spectrum, meaning they fight many types of bacteria, both good and bad. That can lead to development of drug-resistant bacteria, or deadly “superbugs”. This increases the risk for all of us in the future of not having an effective antibiotic to treat our infection.

How do you find out if you have penicillin allergy? Board-certified allergists can test you. First, the allergist will get a history from you about your possible allergy. Typical questions include: How long ago did you have the reaction? What type of reaction occurred, and how soon after you took the penicillin did the reaction appear? The testing is done on the forearm by pricking the skin with a needle. If the results are negative and there is no reaction, penicillin will be injected in the skin. These tests are not painful, and results are available in 15 minutes. A positive reaction may lead to some swelling and itching where the test was placed, which usually goes away within an hour.

In very rare cases, an allergic reaction occurs. This can include hives, swelling, wheezing and/or difficulty breathing. The allergist is trained to treat this rare condition quickly if it happens. If all skin testing is negative, you may be given an oral dose of penicillin in the office. The oral drug challenge is used to verify that you don’t have penicillin allergy. Usually, you’ll be observed in the office for 30 minutes to make sure you have no problems.

If you find out you don’t have a penicillin allergy, notify your physicians that it’s now safe for you to take penicillin. They can take “penicillin allergy” off your chart for good!

【小题1】What can we know about penicillin allergy according to the passage?

A．Most people believe that they are penicillin allergic.

B．People with documented allergy will have it forever.

C．About 90 percent of people are truly penicillin allergic.

D．Many people with initial allergy can avoid it later.

【小题2】Which is NOT the drawback of the alternative antibiotics?

A．They cost much more than penicillin.

B．They can treat many bacterial infections.

C．They can result in drug-resistant bacteria.

D．They also fight good bacteria when used.

【小题3】If you have a positive reaction in skin tests, _______.

A．you can’t leave the office within an hour

B．your skin is supposed to swell and itch

C．it is not safe for you to take penicillin

D．you’ll be given an oral dose of penicillin

【小题4】Which can replace the underlined word “verify”?

A．confirm	B．attach
C．declare	D．control