Stress can cause physical impacts to the body, such as increased heart rate and blood pressure, the release of adrenaline and cortisol (肾上腺素和皮质醇). If adrenaline and cortisol levels are increased for an extended period of time, that can damage DNA and cells.
In a new paper, published in April in the journal Cell Metabolism, researchers described how they measured biological age by looking for changes in DNA’s structure connected to aging.
In the first stage of the research, the researchers surgically attached three-month-old mice to twenty-month-old mice so that blood could flow between them. Over three months, the biological age of the younger mice increased while they shared blood with the older mice. But after the younger mice were separated and allowed to recover for two months, their biological age fell once again.
Then, the researchers looked at human DNA from blood samples gathered in previous studies to measure how human bodies react to stress.
In one stage, the researchers examined blood samples from elderly patients. Patients who had received emergency surgery for a fractured hip (髋部骨折) had an increased biological age the morning after the procedure, but it returned to pre-surgery levels four to seven days later. However, the researchers did not find the same effect in patients who had undergone elective hip surgery or colorectal (结肠直肠的) surgery.
The team also looked at patients who had been hospitalized with Covid-19, but these results varied by sex. While the biological age of female patients dropped within two weeks of recovery, that of men did not.
“The study looked at biological age both before and after stressful events. There are just very, very few studies that have looked at these clocks before and after some kind of intervention (干预),” Daniel Belsky, a medical scientist at Columbia University who did not participate in the study, tells The Scientist.
The study shows that biological age is “much more dynamic than people previously thought,” Jesse Poganik, a co-author of the study, tells Live Science. “You can have these very severe stress events, which increase biological age, but it can be short-lived, if the stress is short-lived, then the age can be restored.”
【小题1】What did the researchers find about the biological age of the younger mice?A.It increased during blood sharing. |
B.It could be restored by blood sharing. |
C.It dropped when they were attached to the older mice. |
D.It returned to pre-sharing levels as soon as they were separated. |
A.Those who had had fractured hip surgery. |
B.Those who had received colorectal surgery. |
C.Those who had undergone elective hip surgery. |
D.Those women who had been hospitalized with Covid-19. |
A.It stands out in similar studies. | B.It is truly remarkable. |
C.It has some limitations. | D.It is influential. |
A.Biological age can be measured easily |
B.Recovering from stress is a long process |
C.Stress ages you with not permanent effect |
D.Stress’ harming human bodies means protecting them well |
A research by Dr. Gail Heyman has confirmed 4- and 5-year-old children who understand people’s beliefs can be false are more likely to lie in experiments than children who still view minds as containing direct copies of reality. When researchers give children experiences to speed up the development of their understanding of the subjective nature of beliefs, these children begin to be untruthful when they would not yet otherwise do so. Although lying is something to be discouraged, the child’s underlying insight into how minds work is an important accomplishment.
In this study, we asked children to teach another child how to turn on a new toy. The toy would turn on when certain blocks— but not others— -were placed on top. Sometimes we asked children to teach the other child the whole truth of how the toy worked; for instance, that all red blocks— regardless of their shape— would turn it on. Other times we asked them to trick the other child into thinking something that was still accurate, but more limited; for example, that the red squares would start the toy (but not necessarily the other red shapes) .
Children in this study carefully considered both the other child’s beliefs and the message we asked them to communicate when deciding what to do. Children who were asked to teach the whole truth often chose to show the other child that a red circle and a red square would both turn on the toy. By choosing two different shapes, they communicated that red blocks would turn on the toy, regardless of shape. These children could have chosen two blocks of the same shape instead; showing that two red squares turn on the toy would also have been an accurate demonstration. But this information could have given rise to the mistaken belief that only red squares would work. The children cleverly avoided showing this type of misleading (though still accurate) information. Instead, they systematically chose the samples that conveyed accurate messages to their partners.
In contrast, when children were asked to lie, they often chose the two red squares. Children had no problem picking the blocks that efficiently conveyed the tricky message when their goal was to lie.
Being able to guess what someone else is thinking and being able to know how to influence someone else’s beliefs are at the root of lying, but of effective communication and social interaction as well.
【小题1】What may turn children into liars according to Dr. Gail Heyman?A.Limited contact with nature. | B.Insufficient parental guidance. |
C.Frequent exposure to false beliefs | D.Precise recognition of one’s hidden intention. |
A.To show the plan of the experiment. | B.To compare children’s different beliefs. |
C.To present the result of the experiment. | D.To tell the detailed process of the experiment |
A.Using two red circles. | B.Picking out two red squares. |
C.Selecting a red circle and a red square. | D.Choosing two red blocks of different sizes. |
A.Lies can never cover the truth. | B.Effective communication kills lies. |
C.Adults are to blame for telling lies. | D.Lying can have a positive outcome. |
Flextime is a flexible hours schedule in which employees choose their own working hours, usually working within approximate limits set by the employer or by the government.
For employees, flextime has a clear advantage.
Most flextime schedules include core time.
A classic example of a flexible time schedule is that someone who works four 10-hour shifts a week can take three days off. Flextime can also be combined with flexplace, in which the environment is better than that of the office.
A.For example, home offices are increasingly popular among many companies. |
B.It allows them to make changes to their work schedule which will suit their lives. |
C.Many employers all over the world offer this method to their employees. |
D.However, flextime may not be applicable to all fields. |
E.It is a period of the day in which everyone is expected to be at work. |
F.Employers benefit from flextime a lot. |
G.It’s also seen as a family-friendly policy. |
Scientists in China found a fossil(化石)from a giant panda that lived 22,000 years ago. Until they dug the fossil out, rebuilt it and analyzed its mitochondrial DNA, biologists had no idea this panda lineage(家系)even existed. It’s now considered the oldest DNA from giant pandas to date, the researchers said.
The panda fossil turned up in Cizhutuo Cave in Guangxi. No pandas live there today, the researchers from the Chinese Academy of Sciences wrote in a paper in the journal Current Biology. An unexpected giant-panda fossil find was exciting, they wrote, because researchers don’t have a good sense of the history of the 2,500 giant pandas alive in the world today. Researchers know that 20 million years ago, the current group of living giant pandas split away(分离)from all other bears. They don’t know much about their lineage since.
This fossil, the researchers showed, came from a creature that separated from living giant pandas much more recently: about 183,000 years ago.
Before the researchers could determine that timeline, though(and, in fact, before they were certain the fossil came from a different species), they had to rebuild the tiny pieces of mitochondrial DNA that remained in the cave. To pull that off, researchers fit 148,329 pieces of DNA together like puzzle pieces, using a living giant panda’s mitochondrial DNA as a guide. All of the pieces came from one individual, and all together, the researchers were able to use them to analyze the animal’s lineage.
The DNA also had dozens of transformations(改变)that would have changed how the animal developed, the researchers said. They suggested those transformations may be the result of adaptation to the cooler climate during the ice age 22,000 years ago.
【小题1】What could scientists do with the help of the giant-panda fossil?A.Find more of the old giant pandas in Cizhutuo Cave. |
B.Understand the living giant pandas’ lineage better. |
C.Know why just 2,500 giant pandas are alive at present. |
D.Publish more papers in the journal Current Biology. |
A.2,500. | B.22,000. |
C.148,329. | D.183,000. |
A.As a way to analyze the mitochondrial DNA. |
B.As a guide to rebuild the mitochondrial DNA. |
C.As a tool to dig the fossil of the creature. |
D.As a timeline to track the history of living giant pandas. |
A.To develop stronger and taller. | B.To show the lineage to scientists. |
C.To live through the severe climate. | D.To split from current living pandas. |
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