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Human-like parts have been grown on the backs of mice using 3D printing. The technique could potentially be used to construct new parts or other body parts in people without the need for surgery.

It's getting more common to see customized body parts, like jaws, ribs and spinal vertebrae built by 3D printing. But these parts must be printed outside the body before they are implanted through surgery, which carries an infection risk.

Now, Mailing Gou at Sichuan University, China, and his colleagues have shown that body ports can be 3D printed inside the body, at least in mice, without the need for surgery.

Initially, the researchers injected a “bio-ink” made of hydrogel particles and cartilage cells into the backs of mice. Next, the bio-inks were exposed to the ear-shaped patterns of near-infrared light. This critical step allowed the hydrogel particles to stick together and develop layer-by-layer into parts-shaped structures. Over the next month, the cartilage cells grew around the hydrogel structures, eventually creating structure similar to the cartilage structures of real human cars. Throughout the process, the mice experienced no significant side effects.

The famous Vacanti mouse of the 1990s also had a human-like ear grown on its back, but it was made by implanting a pre-made plastic structure seeded with cartilage cells underneath the skin, rather than 3D printing the structure directly at the site.

The researchers hope the new technique could be used to construct new ears for people born with microtia, a condition that prevents the parts from developing properly. “We are making effort improve this technique for future treatment of human ear defects,” says Gou.

The nonsurgical 3D printing technique could also potentially be used to repair damaged cartilage in noses, fingers, toes or elbows, says Derek Rosenzweig at McGill University in Canada. In contrast, hip and deep knee cartilage defects may be harder to fix, because near-infrared light usually only penetrates about 2 centimeters into the body, he says.

Gou’s team hopes to eventually adapt the technique to fix other damaged organs like the heart or lungs. However, “this will be more challenging because the heart and lungs contain multiple cell types, which are deeper in the body and are constantly contracting and relaxing,” says Rosenzweig.

【小题1】What is special about the new 3D technique?
A.It requires new surgical methods.B.It causes unexpected side effects.
C.It produces many customized body parts.D.It allows new body parts to grow in the body.
【小题2】According to the passage, which of the following matters most in the experiment process of Gou’s team?
A.The hydrogel particles.B.The cartilage cells.
C.The near-infrared light.D.The pre-made plastic structure.
【小题3】What does Rosenzweig think of the technique?
A.It's life-saving.B.It needs improving.
C.It’s still impossible.D.It’s getting common.
【小题4】What is the best title for the text?
A.New Method of Constructing Body Parts.B.A Breakthrough in Treating Body Defects.
C.A New Technique Requiring No Surgery.D.Body Parts Can Be 3D-Printed Inside the Body.
20-21高三·广东·阶段练习
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More than one billion young people risk damaging their hearing through excessive (过度的) use of smartphones and other audio devices (音频设备), the UN warned Tuesday, proposing new safety standards for safe volume levels.

In order to safeguard hearing, the World Health Organization and International Telecommunications Union issued a voluntary international standard for the manufacture and use of audio devices.

Young people are particularly prone to get risky listening habits. Around half of those between the ages of 12 and 35, or 1.1 billion people, are at risk due to “long exposure to loud sounds, including music they listen to through personal audio devices”, the UN health agency said.

Currently, about five percent of the global population, or some 466 million people, including 34 million children, suffer from disabling hearing loss. WHO considers a volume above 85 decibels (分贝) for eight hours or 100 decibels for 15 minutes as unsafe.

WHO is calling for parental as well as automatic volume controls on audio devices to prevent dangerous use.

While some smartphones and other audio devices already offer some of these features, the UN would like to see a uniform standard used to help protect against disabling hearing loss.

“Think of it like driving on a highway, but without a speedometer (速度计) in your car or a speed limit,” Shelly Chadha of the WHO told reporters in Geneva. “What we’ve proposed is that your smartphones come fitted with a speedometer, with a measurement system which tells you how much sound you’re getting and tells you if you are going over the limit.”

【小题1】What does the underlined word “prone” in paragraph 3 probably mean?
A.Likely.B.Addicted.C.Willing.D.Expected.
【小题2】How do paragraphs 3 and 4 develop?
A.By making comparisons.B.By offering examples.
C.By analyzing reasons.D.By giving figures.
【小题3】Which of the following statements is true according to the passage?
A.Half of 1.1 billion people are getting risky listening habits.
B.About 466 million children are suffering from hearing loss.
C.A volume above 85 decibels for 10 hours or 120 decibels for 15 minutes is unsafe.
D.A uniform standard has been made to help protect against disabling hearing loss.
【小题4】Why does the author mention “driving on the highway” in the last paragraph?
A.To indicate it is dangerous to drive on the highway.
B.To suggest a speedometer should be fitted in a car.
C.To show how a smartphone works with a measure system.
D.To emphasize that it is necessary to fit a measure system in smartphones.

Perhaps you use your headphones to enjoy music and peace and quiet during the day. But you may be neglecting the dangers of hearing loss with headphones. 【小题1】 This is 30% higher than just 20 years before, and experts are pinning it on headphones.

In fact, headphones are not a bad thing. They can bring peace, allow for better musical enjoyment, and even protect your ears from higher decibels(分贝). 【小题2】

How long should you wear your headphones every day? The answer is, according to the World Health Organization, one hour per day. 【小题3】 But the fact is that the longer you listen, you’re going to lose your hearing sooner. To keep hearing loss from happening to you, you should follow the recommendation in place by the WHO that you keep your time with headphones on limited to one hour per day.

Then, how do you set the safest volume for your headphones? With headphones, it depends on the type you’re using and your environment. To test things out, you should take them off your ears and extend them in your hands out in front of you. 【小题4】 If you are using open-back headphones, you should try to have a conversation with someone nearby. When you’re able to carry on the conversation clearly, you’re listening at a proper volume. But do remember that never raise the volume on your listening device over 60% of the maximum!

【小题5】 At others this loss will build up over time. It usually isn’t noticeable in the beginning. It’s not until it’s too late that most people realize that the damage has been done. The only way to know for sure is to consult your doctor.

A.This might seem unreasonable to you.
B.At times, hearing loss isn’t permanent.
C.l in 5 teens will have some types of hearing loss.
D.What’s more concerning is what that means for children.
E.It’s the duration and volume that cause the problem, however.
F.If you still hear your music clearly, you need to turn them down.
G.It’s a wonderful thing to shut out the rest of the world and enjoy your music.

Bad teeth can be painful and even be deadly. Infections of the gums (牙龈) and teeth can release bacteria into the blood system. Those bacteria can increase the chance of a heart attack or stroke and worsen the effects of other diseases. And adults are not the only ones at risk. For example, a 12­-year-­old   boy died when a tooth infection spread to his brain in 2007 in Washington. Experts said it might have been prevented had he received the dental care he needed.

Experts say good dental care starts at birth. Breast milk,they say,is the best food for the healthy development of teeth. Breast milk can help slow bacterial growth and acid production in the mouth. But dentists say a baby’s gums and early teeth should be cleaned after each feeding by using a cloth with a little warm water. Experts say if you decide to put your baby to sleep with a bottle, give only water.

When baby teeth begin to appear,you can clean them with a wet toothbrush. Dentists say it is important to find soft toothbrushes made especially for babies and to use them very gently. The use of fluoride (氟化物) to protect teeth is common in many parts of the world. For example, it is often added to drinking water supplies. The fluoride mixes with enamel (釉质),the hard surface on teeth, to help prevent holes from forming.

But young children often swallow toothpaste when they brush their teeth. The American Academy of Pediatric Dentistry notes that swallowing fluoridated toothpaste can cause problems. So young children should be carefully watched when they brush their teeth. And only a small amount of fluoridated toothpaste, the size of a pea, should be used.

Parents often wonder what effect finger sucking might have on their baby’s teeth. Dental experts generally agree that this is fine early in life. Most children stop sucking their fingers by the age of four. If it continues,experts advise parents to talk to their children’s dentists or doctors because it could interfere with the correct development of permanent teeth.

Dentists say children should have their first dental visit at least by the time they are one year old. They say babies should be examined when their first teeth appear—usually at around six months.

【小题1】What’s the main idea of the first paragraph?
A.Bad teeth can be a threat to people’s health.
B.Bad teeth come along with other health problems.
C.Tooth infections can spread to brain easily.
D.Dental care should be done at an early age.
【小题2】According to the passage, what is the function of fluoride?
A.Making the surface on teeth much cleaner.
B.Protecting gums from being infected.
C.Keeping holes on teeth from forming.
D.Slowing down bacterial growth and acid production.
【小题3】What is the purpose of the author in writing the passage?
A.To warn us of the deadly infections of gums and teeth.
B.To introduce the advantages of fluoridated toothpaste.
C.To draw our attention to the dental care of young children.
D.To present the research results about dental care.

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