Why elephants rarely get cancer is a mystery that has confused scientists for decades. A study led by researchers at Huntsman Cancer Institute (HCI), at the University of Utah and Arizona State University may have found the answer.
According to the results, elephants have 38 additional modified copies of a gene that encodes p53, a definite tumor suppressor, as compared to humans, who have only two. Further, elephants may have a more powerful mechanism for killing damaged cells that are at risk for becoming cancerous. In isolated elephant cells, this activity is doubled compared to healthy human cells, and five times that of cells from patients with Li-Fraumeni Syndrome, who have only one working copy of p53 and more than a 90 percent lifetime cancer risk in children and adults. The results suggest extra p53 could explain elephants’ increased resistance to cancer.
“Nature has already figured out how to prevent cancer. It’s up to us to learn how different animals overcome the problem so we can adapt those strategies to prevent cancer in people,” says co-senior author Joshua Schiffman, M.D., pediatric oncologist (儿科肿瘤医生) at Huntsman Cancer Institute, University of Utah School of Medicine.
But Prof Mel Greaves, from the Institute of Cancer Research in London, says we should focus on why humans have such high levels of cancer. He pointed to the rise of unhealthy, cancer-causing behaviors, such as obesity and sunbathing. “You’ve never seen an elephant smoke!” he added.
According to Schiffman, elephants have long been considered a walking problem. Because they have 100 times as many cells as people, they should be 100 times more likely to have a cell slip into a cancerous state and cause the disease over their long life span of 50 to 70 years. And yet analysis of a large database of elephant deaths estimates a cancer death rate of less than 5 percent compared to 11 to 25 percent in people.
【小题1】Why are elephants less likely to get cancer than humans?A.Elephants are bigger than humans. |
B.Elephants have more p53 genes and mechanism killing damaged cells. |
C.Elephants are not as clever as humans in walking. |
D.Elephants eat more than humans. |
A.multiplier | B.complex | C.restrainer | D.coordinator |
A.Doubtful. | B.Neutral. | C.Critical. | D.Favorable. |
A.Elephants have longer life than people. |
B.There is no chance that elephants die from cancer. |
C.The rate of elephants dying from cancer is increasing. |
D.It was thought theoretically that elephants could get cancer more easily. |
Social bond of animals
Friendship is an important part of human life. Friends can share our joys and our hardships. We aren’t alone.
Recently, a British research team finished an eight-year study of Indo-Pacific dolphins off the coast of-Western Australia. These dolphins can use different tools to search for food.
“It suggests that dolphins form social bonds based on shared interests,” UK biologist Simon Allen told Science Daily. “Using different tools is time-consuming for dolphins to cooperate.”
Apart from dolphins, elephants, horses and bats are also known to form friendships.
Of course not, The Atlantic reported. In 2015, a goat was originally left in a tiger’s enclosure (围场) as a meal.
Humans aren’t so different. “We do not work, play and live together with the same friends all the time,” Swiss zoologist Gerald Kerth explained. “But nevertheless, we are able to maintain long term relationships... despite our often highly dynamic social lives.”
A.Many different animals also make friends. |
B.Are friendships only limited to the same species? |
C.Dolphins live on fish but they do not spend all their time looking for fish. |
D.More interestingly, animals not only make friends but also try to keep lasting friendships. |
E.The goat was frightened of the tiger, and pretended to make friends with it for the sake of its own safety. |
F.The researchers found that these dolphins are more willing to hang out with partners that like the same tool. |
G.But instead of eating the goat, the tiger likes to play with it and gets jealous when other animals are close to his friend. |
In most parts of Britain, the black cat is a symbol of good luck and owning a black cat may bring good luck to the family. But recently, black cats can no longer enjoy so much favor.
The Royal Society for the Prevention of Cruelty to Animals (英国防止虐待动物协会) announced a rise in the number of black cats being abandoned by their owners, due to not looking good in selfies (自拍). According to the RSPCA, more than 70 percent of the cats in its care are black. The biggest reason for that is black cats tend not to photograph as their lighter and brighter-colored fellows with more obvious markings. An RSPCA spokesman said, “This has become a national problem. And we are urging people to never judge a cat by its color but look at its personality instead.”
The Millwood Cat Rescue Centre has taken in nice black cats in the past two weeks. The founder of the rescue centre said, “We have had a lot of black cats because people don’t like black at the moment. Other look at the black cats and then just say ‘Oh, have you got anything else?’”
Animal lover Gabriella Fletcher owns a 16-year-old black cat, Susie. She regularly takes selfies with her pet. She said, “It is hard to get a good picture as you can’t really see how beautiful Susie is. She is just as special as any other cat.”
【小题1】Why are black cats less favored by people?A.They are rising in number. | B.They don’t bring good luck anymore |
C.They are banned by RSPCA. | D.They don’t look good in photos. |
A.People want more black cats. | B.People want to have something to eat. |
C.People want more pet animals. | D.People are unwilling to see so many black cats. |
A.disgusting | B.unlucky |
C.ordinary | D.attractive |
A.Black cats out in “selfies”. | B.Black cats abandoned in the UK. |
C.Black cats in need of caring. | D.Black cats favored again. |
One day, while I was walking on the street, I saw a young cat attacking an old cat. I immediately ran to them and drove the young cat away. When I got close to the old cat, I found he had got injured.
I held him in my arms and rushed to the Best Friends Animal Clinic. There he received important medical care. But with a serious infection (感染) in his leg,he was far from out of the woods. He was very sick and in shock. His body temperature was far below normal. He couldn't move and was breathing hard for air. The vet team immediately cleaned his wounds,used medicine to fight off the infection and reduce his pain,and placed him in an oxygen tank. But he was still getting weaker by the minute. At last,the vet team had to remove his damaged and infected leg to save him.
![](https://img.xkw.com/dksih/QBM/2020/12/6/2608481225949184/2608524221300736/STEM/8b87819640174811a77742361c32cf5e.png?resizew=132)
After he recovered,I took him home and named him Tommy. He learned how to ride in a stroller (小推车). Once he got used to the stroller,doors began to open for him. He began going on morning rounds with me. He made a few furry friends,too,including a Chihuahua. He even had a picnic with the Chihuahua on a blanket under the sunny sky.
Though Tommy's life as an outdoor cat may have ended,the medical care he received has made it possible for him to have a whole new life. Now Tommy stays very positive (积极的). He taught me a good lesson—though bad things happen in our life,we should always stay positive and enjoy what we have.
【小题1】The underlined part in Paragraph 2 means that the cat .A.was making a slow recovery |
B.was in great danger |
C.was filled with anger |
D.suffered a lot from his wounds |
A.the cat's body got infected too |
B.the medicine wasn't very helpful |
C.the cat's body temperature became normal |
D.the cat would die unless all his legs were removed |
A.The cat was very clever and friendly. |
B.It took a long time for the cat to recover. |
C.That stroller was of great importance to the cat. |
D.The cat started a new life with the author's help. |
A.We shouldn't be beaten by bad things. |
B.Humans should treat animals kindly. |
C.Bad things can happen to anyone. |
D.Animals are humans' best friends. |
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